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Colgate® Anywhere Anytime® Sensitivity Relief Serum

Rapid relief for sensitive teeth prior to treatment, at-home, and on-the-go. This fast-acting serum works in 1 minute with fingertip application.

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Colgate® Anywhere Anytime® Sensitivity Relief Serum image

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  • Details

  • Product Ingredients

    Arginine bicarbonate, benzyl alcohol, calcium carbonate, cellulose gum, flavor, glycerin, propylene glycol, sodium bicarbonate, sodium saccharin, sodium silicate, titanium dioxide, water

    Package Ingredients:

    Tube: 0.16FL OZ (5mL) Sensitivity Relief Serum

    Package: 24 0.16FL OZ (5mL) Sensitivity Relief Serum Tubes

  • Characteristics

  • Study Results

  • Product Resources

     

  • Indications and Usage

    Anywhere Anytime Sensitivity Relief Serum is intended for single patient use.

    For Dental Professionals:

    • Please use this tube to provide relief from sensitivity prior to professional treatment, per the instructions below. Please provide this same tube to the patient for use post-treatment or as needed.

    Patient Usage Directions:

    1. Apply the gel directly to any sensitive tooth with your fingertip and gently massage for 1 minute.
    2. For best results, focus where your tooth meets your gums and do not rinse after use. Use a pea sized amount and apply as needed

    Important Safety Information:

    • Children and adolescents should consult a dentist or physician prior to use.
    • Sensitive teeth may indicate a serious problem that may need prompt care by a dentist. Stop use and ask a dentist if the problem persists or worsens. If pain/sensitivity still persists after 4 weeks of use, please visit your dentist. Keep out of reach of children.

    Characteristics

    • Exclusive Arginine and Calcium Carbonate technology
    • Convenient tube which can be used in-office chairside, at-home, or on-the-go
    • One package contains 24 individual tubes.

    Benefits

    • Provides sensitivity relief in 1 minute* (*with fingertip application)

  • Characteristics and Benefits

  • How to order

  • Benefits

  • Description

  • Ingredients

    Active Ingredient: Sodium fluoride 1.1% (w/v)

    Inactive Ingredient: Purified water, sorbitol solution 70%, hydroxyethylcellulose, pluronic F-127, flavor, sodium saccharin, methyl paraben, titanium dioxide, propylparaben, certified dyes (FD&C Red #40 In Bing Cherry and Very Berry flavors, FD&C Blue #1 in Fresh Mint flavor)

    Clinical Pharmacology

    Frequent topical applications to the teeth with preparations having a relatively high fluoride content increase tooth resistance to acid dissolution and enhance penetration of the fluoride ion into tooth enamel.

  • Manufacture/Distribution

  • Pharmacokinetics

  • Clinical Pharmacology

  • Contraindications

  • Warnings

    Prolonged daily ingestion may result in various degrees of dental fluorosis in pediatric patients under age 6 years, especially if the water fluoridation exceeds 0.6 ppm. Use in pediatric patients under age 6 years requires special supervision to prevent repeated swallowing of gel. Read directions carefully before using. Keep out of reach of infants and children.

  • Precautions

    General: Not for systemic treatment. DO NOT SWALLOW.

    Carcinogenesis, Mutagenesis, Impairment of Fertility: In a study conducted in rodents, no carcinogenesis was found in male and female mice and female rats treated with fluoride at dose levels ranging from 4.1 to 9.1 mg/kg of body weight. Equivocal evidence of carcinogenesis was reported in male rats treated with 2.5 and 4.1 mg/kg of body weight. In a second study, no carcinogenesis was observed in rats, males or females, treated with fluoride up to 11.3 mg/kg of body weight. Epidemiological data provide no credible evidence for an association between fluoride, either naturally occurring or added to drinking water, and risk of human cancer.

    Fluoride ion is not mutagenic in standard bacterial systems. It has been shown that fluoride ion has potential to induce chromosome aberrations in cultured human and rodent cells at doses much higher than those to which humans are exposed. In vivo data are conflicting. Some studies report chromosome damage in rodents, while other studies using similar protocols report negative results.

    Potential adverse reproductive effects of fluoride exposure in humans has not been adequately evaluated. Adverse effects on reproduction were reported for rats, mice, fox, and cattle exposed to 100 ppm or greater concentrations of fluoride in their diet or drinking water. Other studies conducted in rats demonstrated that lower concentrations of fluoride (5 mg/kg of body weight) did not result in impaired fertility and reproductive capabilities.

    Pregnancy: It has been shown that fluoride crosses the placenta of rats, but only 0.01% of the amount administered is incorporated in fetal tissue. Animal studies (rats, mice, rabbits) have shown that fluoride is not a teratogen. Maternal exposure to 12.2 mg fluoride/kg of body weight (rats) or 13.1 mg/kg of body weight (rabbits) did not affect the litter size or fetal weight and did not increase the frequency of skeletal or visceral malformations. There are no adequate and well-controlled studies in pregnant women. However, epidemiological studies conducted in areas with high levels of naturally fluoridated water showed no increase in birth defects. Heavy exposure to fluoride during in utero development may result in skeletal fluorosis, which becomes evident in childhood.

    Nursing Mothers: It is not known if fluoride is excreted in human milk. However, many drugs are excreted in milk, and caution should be exercised when products containing fluoride are administered to a nursing woman. Reduced milk production was reported in farm-raised fox when the animals were fed a diet containing a high concentration of fluoride (98-137 mg/kg of body weight). No adverse effects on parturition, lactation, or offspring were seen in rats administered fluoride up to 5 mg/kg of body weight.

    Pediatric Use: The use of PreviDent Brush-On Gel in pediatric age groups 6 to 16 years as a caries preventive is supported by pioneering clinical studies with 1.1% sodium fluoride gels in mouth trays in students age 11 to 14 years conducted by Englander et al. 2-4 Safety and effectiveness in pediatric patients below the age of 6 years have not been established. Please refer to the CONTRAINDICATIONS and WARNINGS sections.

  • Adverse Reactions

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  • How Supplied

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