

Keep your patients on track between visits

Left uncontrolled, bacterial biofilm puts patients at risk1
It’s difficult for even the most diligent of patients to control biofilm at home.2

Brushing alone
reduces bacterial plaque by ONLY 42%*3

Not all toothpastes are equally
effective in actively preventing oral health problems†4

Only 1 in 4 patients uses
mouthwash regularly5
*After a single brushing session with a manual toothbrush.
†Such as gingivitis, tooth sensitivity, tartar and malodor vs non-antibacterial fluoride toothpaste..
To offer more biofilm control, get a better daily system going.*

*Up to 15x more effective at fighting the root cause of many common oral health issues such as gingivitis or cavities by reducing bacteria buildup in 6 weeks
starting in week 1, vs non-antibacterial fluoride toothpaste and flat trim toothbrush, when used together.
†vs an ordinary flat-trim toothbrush.
‡Twice-daily use will help prevent oral care problems caused by bacteria like: plaque, gingivitis, cavities, and bad breath.

Data supports the Colgate Total® Active Prevention System
15x more effective at fighting the root cause of many oral health problems when used together*

*15x more effective at fighting the root cause of many common oral health issues such as gingivitis or cavities by reducing
bacteria buildup in 6 weeks starting in week 1, vs non-antibacterial fluoride toothpaste and flat-trim toothbrush, when used together
References: 1. Ledder RG, Latimer J, Forbes S, Penney JL, Sreenivasan PK, McBain AJ. Visualization and quantification of the oral hygiene effects of brushing, dentifrice use, and brush wear using a tooth brushing simulator. Front Public Health. 2019;7:91. 2. Ray RR, Pattnaik S. Technological advancements for the management of oral biofilm. Biocatalysis Agricultural Biotechnol. 2024;56(6):103017. 3. Chapple IL, Van der Weijden F, Doerfer C, et al. Primary prevention of periodontitis: managing gingivitis. J Clin Periodontol. 2015;42(suppl 16):S71-S76. 4. Clark-Perry D, Levin L. Comparison of new formulas of stannous fluoride toothpastes with other commercially available fluoridated toothpastes: a systematic review and meta-analysis of randomised controlled trials. Int Dent J. 2020;70(6):418-426. 5. McFarlane TV, Kawecki MM, Cunningham C, et al. Mouthwash use in general population: results from Adult Dental Health Survey in Grampian, Scotland. J Oral Maxillofac Res. 2011;1(4):e2. 50. 6. Seriwatanachai D, Mateo LR, D’Ambrogio R, Xu G, Zhang YP, Gittins E. Clinical results of 4 week antibacterial study for stannous fluoride toothpaste. J Dent Res. 2024;103(Spec Iss A):1082. 7. Gittins A, et al. Efficacy of a stannous fluoride toothpaste stabilized with K+ and polyphosphates (SNAP) on immediate tooth sensitivity relief. J Dent Res. 2022;101(Spec Iss A):0512. 8. Rajah L, et al. Stannous fluoride vs regular fluoride dentifrice in plaque and gingivitis reduction. J Dent Res. 2022;101(Spec Iss A):0514. 9. Monty H, et al. Clinical investigation on oral malodor for new formula of stannous toothpaste as compared to Colgate Cavity Protection Toothpaste using organoleptic method. J Dent Res. 2024;103(Spec Iss A):1167.