The unique formula of Colgate Total® toothpaste has an antibacterial system comprising 0.3% triclosan and 2% copolymer, as well as 1100 ppm fluoride. Its copolymer ensures the effective delivery and retention of triclosan on oral hard and soft tissues, so that it keeps working between brushings to provide up to 12 hours of antibacterial protection. Colgate Total® is also clinically proven to reduce calculus build up and oral malodor.
Colgate Total® is unique because it is the only toothpaste formulated with 0.3% triclosan and 2% copolymer for anti-plaque and anti-gingivitis benefits, in addition to its 1100 ppm fluoride for anti-caries efficacy. Colgate Total® toothpaste is clinically proven to work better than other toothpastes in controlling oral bacteria that form plaque and can cause gingivitis. Additionally, Colgate Total® , with its active ingredient triclosan, has been approved as safe and effective by the U.S. Food and Drug Administration (FDA) via its rigorous New Drug Application (NDA) process. This is the same process used by the FDA to approve prescription medications, and Colgate Total is the only toothpaste on the market that has undergone the FDA's NDA review process. It is also the only toothpaste that is both approved by the FDA and accepted by the American Dental Association as safe and effective in helping to prevent gingivitis.
The triclosan in Colgate Total® is a broad spectrum antibacterial ingredient effective against plaque and gingivitis. The copolymer is used in the formulation to ensure the effective delivery and retention of the triclosan on oral hard and soft tissues, and on plaque. This results in 12-hour antibacterial protection.
Prior to first marketing Colgate Total® in 1997, we had to submit a New Drug Application (NDA) to the United States Food and Drug Administration (FDA). This was necessary because Colgate Total® contained a new combination of ingredients in the product, made new product claims, and provided consumers with new benefits. FDA's review successfully concluded with the approval of the NDA for Colgate Total® toothpaste, which means that the FDA determined that Colgate Total® was safe and effective for its intended use. The NDA for Colgate Total® was approved on July 11, 1997.
Colgate Total® provides therapeutic benefits against caries, plaque, and gingivitis. In addition, it is effective in reducing supragingival calculus and oral malodor. You can recommend Colgate Total® with confidence to all your patients who are in need of plaque and gingivitis protection. Note: Gingivitis is not prevalent in children under 6 years old. Therefore Colgate Total® has not been tested in this age group of consumers and is not recommended for plaque and gingivitis protection in children under 6 years of age.
A thorough independent review was conducted and published by the Cochrane Oral Health Group on the oral health benefits of triclosan/copolymer, the active antibacterial system in Colgate Total® toothpaste. The Cochrane Review evaluated 30 studies dating from 1990 to 2012 and involving 14,835 participants (Riley & Lamont 2013). The resulting data highlighted the many clinical benefits of using a fluoride toothpaste containing triclosan/copolymer and concluded there was no evidence of any harmful effects associated with the use of triclosan/copolymer toothpastes in studies up to three years in duration. Among other things, the Cochrane Review found that after six or more months of use, fluoride toothpaste containing triclosan/copolymer provided:
The efficacy and safety of Colgate Total® is supported by more than 90 clinical studies, involving over 20,000 people, and a broad set of safety evaluations. Our research has been shared with regulatory agencies around the world who have accepted triclosan’s safe and effective use in toothpaste.
For additional information, see http://www.fda.gov/ForConsumers/ConsumerUpdates/ucm205999.htm
Colgate Total® has a 2-year expiration date, the same shelf-life as other Colgate toothpastes. The 0.75 oz sample tubes of Colgate Total® have a shelf life of 18 months.
Colgate Total® is formulated with 0.243% sodium fluoride for anti-caries efficacy. This translates to 1,100 ppm (parts per million) of fluoride ion.
Colgate Total® is indicated as a daily use toothpaste. There is no contraindication against prolonged use. Colgate Total® should be used as directed for adults and children older than 6 years of age.
Consult your doctor or physician.
As with any product, if you are pregnant or nursing, your medical professional is always the best source of advice on the use of consumer products.
Children under 6 years should not use Colgate Total® unless directed by a dentist or physician, as anti-gingivitis and anti-plaque effects have not been proven in children.
Abrasives are ingredients in toothpastes which are needed to remove debris, plaque and/or stains. They also help polish and brighten the surface of your teeth. The abrasivity of a toothpaste is measured using the RDA (Relative Dentin Abrasivity) value. All Colgate toothpastes fall well under the maximum RDA value of 250 allowed by the American Dental Association (ADA).
For RDA information on specific Colgate Toothpastes, please call us at 1-800-468-6502, Monday-Friday, 9:00am - 5:30pm EST